By: Ed Susman
ATLANTA, GA – Patients who undergo radical cystectomy with robot-assisted technology appear to have survival rates similar to those of patients who are treated with the gold-standard open operations, researchers said here at the American Urological Association 2012 Annual Scientific Meeting.
“Overall survival was not different when looking at different surgical approaches,” said Kyle Richards, MD, Wake Forest University Baptist Hospital, Winston-Salem, North Carolina, “Bladder cancer-specific survival was not different either.”
Dr. Richards reported on survival outcomes among 225 bladder cancer patients. Of those with more than 6 months of follow-up, 97 patients underwent radical cystectomy with robot technology and were compared with 100 patients who had undergone open surgery. There were no statistical differences in pathological characteristics between the 2 patient groups.
“Hospital stay was a little bit less for the robotic group [6 vs 8 days],” Dr. Richards said. “Other groups have shown the same thing. We did not conduct a quality-of-life analysis.”
Twelve-month survival among the patients treated with the robot was 76%, versus 77% among patients who underwent open surgery. After 24 months, the overall survival among the robot-assisted patients was 69%,versus 64% for those undergoing open surgery, which was not statistically different (P[/i> =.35).
The bladder cancer-specific survival after 1 year was 81% among patients who were operated on with the robot versus 88% among those undergoing open surgery. After 2 years, the bladder cancer-specific survival was 75% in the robot-assisted group and 80% in the open surgery group (P =.11).
Among patients with positive lymph nodes, overall survival was decreased in both groups: 25% survived at least 2 years in the robot-assisted patient group, and 38% survived among patients who had open surgery (P =.09).
About 70% of the patients in the study were men. The median age was 67 years. Body mass index was about 27. Positive margins were observed in 10% of patients in each group. About 10% of patients were treated with neoadjuvant systemic chemotherapy. Robotic cystectomy has been performed at Wake Forest since 2008. The comparative open surgeries were performed from 2005 through 2011.
- MFP Wire Services